Senior Scientist, Bioanalytical Sciences
Annexon Biosciences is a clinical-stage biopharmaceutical company developing a new class of complement medicines for patients with classical complement-mediated autoimmune, neurodegenerative, and ophthalmic disorders of the body, brain, and eye. The company’s pipeline is based on its platform technology addressing a broad spectrum of well-researched classical complement-mediated autoimmune and neurodegenerative diseases triggered by aberrant activation of C1q, the initiating molecule of the classical complement pathway. Annexon is advancing a portfolio of innovative product candidates designed to block the activity of C1q and the entire classical complement pathway: ANX005 (intravenous administration), ANX007 (intravitreal administration), and ANX009 (subcutaneous administration). Annexon is deploying a disciplined, biomarker-driven strategy designed to improve the probability of technical success of its portfolio.
Desired Candidate Profile
We are seeking a highly motivated and experienced Senior Scientist to join the bioanalytical team. Qualified candidates must have extensive experience developing and implementing ligand binding (ELISA, MSD) assays for PK, ADA, and biomarkers that support preclinical and clinical programs. Cell-based assay experience is highly desirable. The ideal candidate will have experience at a level to provide scientific leadership to bioanalytical staff scientists in assay development, troubleshooting, and data interpretation. Broad experience with other technologies such as SPR (Biacore), and strategies for electronic data capture and laboratory automation is highly desirable. The candidate will work as part of broader, highly collaborative, interdisciplinary team in a fast-paced research & development environment. In addition, the candidate should have a solid understanding of the drug development paradigm from research through clinical development, experience with GxP compliance requirements and FDA regulatory guidelines as applicable in support of drug development programs. Experience with all aspects related to the bioanalytical flow from discovery to production including technology transfer and oversight of the Sponsor-CRO relationship is highly desirable.
Annexon’s Senior Scientist, Bioanalytical Sciences will be required to be fully vaccinated against the Covid-19 virus. An applicant is considered fully vaccinated two weeks after their second dose in a 2-dose series, such as the Pfizer or Moderna vaccines, or two weeks after a single-dose vaccine, such as Johnson & Johnson’s Janssen vaccine. You will be required to show proof of vaccination status upon hire. The Company provides reasonable accommodations in accordance with applicable state, federal and local laws.
Annexon is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status.